• P-ISSN 0974-6846 E-ISSN 0974-5645

Indian Journal of Science and Technology

Article

Indian Journal of Science and Technology

Year: 2019, Volume: 12, Issue: 10, Pages: 1-5

Original Article

CSTNPD: A Database for Cancer Specific Toxic Natural Products

Abstract

Objective: To compile an open access central resource database for cancer specific toxic natural products. Methods: The literature survey using PubMed was made manually in order to collect the natural product that exhibit anticancer activity but not or least toxic to normal cell, and were curated by in an open access central resource database. Result: The compound database provides opportunities for researchers to obtain various information required for the successful identification of pharmaceutically relevant substances. Application: The bioactive natural products with anticancer therapeutic potential are abundantly reported, but majority of them are toxic to normal cells too. All those novel natural product molecules failed to proceed towards further detailed research or to reach into clinical trial and pharmaceutical drug development and drug approval.

Keywords: Cancer, Database, Natural Products, Plants, Toxic, CSTNPD

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