Indian Journal of Science and Technology
DOI: 10.17485/ijst/2019/v12i10/141396
Year: 2019, Volume: 12, Issue: 10, Pages: 1-5
Original Article
Mohammad Ajmal Ali1, Mohammad Tabrez Quasim2*, Mohammad Abul Farah3, Fahad Mohammad Al-Hemaid1, Joongku Lee4, Khalid Mashay Al-Anazi3, Soo Yong Kim5 and Tapan Pan6
1Department of Botany and Microbiology, College of Science, King Saud University, Riyadh- 11451, Saudi Arabia; [email protected], [email protected]
2Department of Computer Science, College of Computing & Information Technology, University of Bisha, Bisha - 61361, Saudi Arabia; [email protected]
3Department of Zoology, College of Science, King Saud University, Riyadh- 11451, Saudi Arabia; [email protected], [email protected]
4Department of Environment and Forest Resources, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea; [email protected]
5International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon- 305 806, Republic of Korea; [email protected]
6University Department of Botany, Tilka Manjhi Bhagalpur University, Bhagalpur - 812007, Bihar, India; [email protected]
*Author for correspondence
Mohammad Tabrez Quasim
Department of Computer Science, College of Computing & Information Technology, University of Bisha, Bisha - 61361, Saudi Arabia.
Email: [email protected]
Objective: To compile an open access central resource database for cancer specific toxic natural products. Methods: The literature survey using PubMed was made manually in order to collect the natural product that exhibit anticancer activity but not or least toxic to normal cell, and were curated by in an open access central resource database. Result: The compound database provides opportunities for researchers to obtain various information required for the successful identification of pharmaceutically relevant substances. Application: The bioactive natural products with anticancer therapeutic potential are abundantly reported, but majority of them are toxic to normal cells too. All those novel natural product molecules failed to proceed towards further detailed research or to reach into clinical trial and pharmaceutical drug development and drug approval.
Keywords: Cancer, Database, Natural Products, Plants, Toxic, CSTNPD
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