Indian Journal of Science and Technology
Year: 2020, Volume: 13, Issue: 29, Pages: 2935-2940
Mohammed F ElMohr1*, Mohamed Faris1, Sayed Bakry2, Heba Hozyen3,Fathy M Elshaer4,5
1Dr Faris Medical Center for Infertility and Human Reproduction, Heliopolis, Cairo, Egypt
2Laboratory of Molecular Biology and Embryology, Zoology Department, Faculty of Science,Al-Azhar University, Nasr City, Cairo, Egypt
3Animal reproduction & Artificial Insemination Department, Veterinary Research Division,National Research Centre, Dokki, Cairo, Egypt
4Department of Biology, College of Science, Jouf University, Sakaka, Saudia Arabia
5Zoology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt
Email: [email protected]
Received Date:26 May 2020, Accepted Date:27 July 2020, Published Date:11 August 2020
Purpose: To assess the effects passive smoking and heavy metal concentrations in the blood and follicular fluid on assisted reproductive technology outcome.Methods: A prospective study was conducted between March 2017 and January 2018 in population consisted of 75 female patients undergoing an In vitro fertilization (IVF) cycle at Dr. Faris Medical center for Infertility and Human Reproduction located on Heliopolis, Cairo, Egypt; with unexplained infertility who underwent intracytoplasmic sperm injection (ICSI) using GnRH-antagonist protocol. Concentrations of three toxic metals Cadmium (Cd), Lead (Pb) and Arsenic (As) were measured both in blood sera and follicular fluid specimens. Patients were evaluated in two groups both undergoing ICSI; the first group consisted of patients who does not smoke or exposed to smoking (n=28) and the group passive smoker females (n=47). Results: These three heavy metals were significantly higher in serum and follicular fluid of passive smoking females (P<0.05). Also, higher concentrations of Cd, Pb and As were found in follicular fluid of passive smoking patients in comparison with non-smoker females. However, concentrations of Cd and Pb were not significantly different between both serum and follicular fluid. Conclusion: Passive smoking could affect levels of Cd, Pb and As in serum and follicular fluid of females undergoing Intra Cytoplasmic Sperm Injection (ICSI).
Keywords: Cadmium (Cd); Lead (Pb); Arsenic (As); Follicular fluid (FF); Intra Cytoplasmic Sperm Injection (ICSI); heavy metals
© 2020 ElMohr et al..This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Indian Society for Education and Environment (iSee).
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