Indian Journal of Science and Technology
DOI: 10.17485/ijst/2013/v6i6.2
Year: 2013, Volume: 6, Issue: 6, Pages: 1-4
Original Article
A. M. Sabitha Rani 1* and K. Murugesan2
1 Faculty, Department of Biotechnology, [email protected]
2 Centre for Advanced Studies in Botany, [email protected]
*Author For Correspondence
A. M. Sabitha Rani
Department of Biotechnology,
Email:[email protected]
The aim of the present research was focused on the antiviral properties of Vicoa indica (L.) via in vitro approach. The aqueous and methanolic extracts from leaves, stems and roots of V. indica (Asteraceae) were tested against HSV – 1 replication. Among these extracts, aqueous extract of roots was found to have more potent inhibitory effect. The less concentration (20µg/mL) of methanolic extracts was cytotoxic to vero cell lines. The used concentrations of aqueous extracts were 100 - 50µg/mL. We determined that extract obtained from root has higher antiviral effect, and it causes 100 per cent decrease of the virus at IC50 of 100 and 50µg/mL respectively. Further research is needed to elucidate the active constituents of this plant may be useful in the development of new and effective antiviral agents.
Keywords: Asteraceae, Aqueous Extracts, Vicoa indica, HSV–1
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