Indian Journal of Science and Technology

Abstract

Objectives: This study was undertaken with the objective of studying the effect of selenium nanoparticles on oxidation resistance in broiler chicken. Methods: An in vivo feeding experiment was conducted in 150 broiler chicks. three replicates of 10 birds were maintained for each treatment with various levels of selenium nanoparticles (0.075, 0.1125. 0.1875 and 0.225 mg/kg ) along with selenium coarse particles (0.15 mg/kg) as control group. The serum samples obtained from different treatments were subjected to analysis of antioxidant enzymes. The data obtained were analysed with ANalysis Of VAriance (ANOVA). Findings: Birds supplemented with 0.1875 mg/kg selenium nano-particles showed a significant (p < 0.05), increase in serum superoxide dismutase activity and glutathione peroxidase activity and decrease in malondialdehyde concentration. But, when the dietary level of Selenium Nanoparticles was increased to 0.225 mg/kg, level of superoxide dismutase and glutathione peroxidase activities in serum got significantly (p < 0.05) reduced and the concentration of malondialdehyde increased when the levels were compared to the control group and remaining treatment groups. So it is concluded that selenium nanoparticles of level 0.1875 mg/kg feed improved the activities of antioxidant enzymes and thus the oxidation resistance in broiler chicken but when the selenium nanoparticles were supplemented at a level of 0.225 mg/ kg feed it reduced the level of antioxidative enzymes in broiler chicken. Application: The selenium nanoparticles can be used to improve the oxidation resistance in broiler chicken. Keywords: Antioxidant Enzymes, Broiler Chicken, Oxidative Resistance, Selenium Nanoparticles