Phytochemical analysis and anti-diabetic activity of Cadaba fruticosa R.Br.

S  Arokiyaraj; R  Radha; S  Martin  and K  Perinbam

doi:10.17485/ijst/2008/v1i6.8

Article

Phytochemical analysis and anti-diabetic activity of Cadaba fruticosa R.Br.

VIEWS 1186
PDF 399

Abstract
Full-Text HTML
Full-Text PDF
How to Cite

Indian Journal of Science and Technology

DOI: 10.17485/ijst/2008/v1i6.8

Year: 2008, Volume: 1, Issue: 6, Pages: 1-4

Original Article

Phytochemical analysis and anti-diabetic activity of Cadaba fruticosa R.Br.

S. Arokiyaraj¹ , R. Radha^2*, S. Martin³ and K. Perinbam¹

¹PG & Research Sathyabama University, Chennai-119, India.
²Department of Pharmaceutical Sciences, Madras Medical College, Chennai-3.
³Jaya College of Engineering, Thiruninravur, Chennai-602024

*Author for the correspondence:
R. Radha,
Department of Pharmaceutical Sciences,
Madras Medical College, Chennai-3.
E-mail: [email protected]

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Alcohol and aqueous extract of Cadaba fruticosa (leaves) were subjected for hypoglycemic activity in wistar rats (160-200 g). The oral administration of leaf extracts at dose 1000 mg/kg led to a significant blood glucose reduction. Phytochemical analysis of alcohol extract revealed the presence of terpenoids, flavanoids, steroids, proteins, alkaloids, gums, sugars and saponins but negative result was observed in aqueous extract except terpenoids, flavonaids, proteins, furans, gums and sugars. This study brings out the evidence regarding pharmacological and phytochemical activities of C. fruticosa.

Keywords: Acute toxicity, anti-diabetic, alloxaninduced diabetes, Cadaba fruticosa