Indian Journal of Science and Technology
Year: 2008, Volume: 1, Issue: 6, Pages: 1-4
S. Arokiyaraj1 , R. Radha2*, S. Martin3 and K. Perinbam1
1PG & Research Sathyabama University, Chennai-119, India.
2Department of Pharmaceutical Sciences, Madras Medical College, Chennai-3.
3Jaya College of Engineering, Thiruninravur, Chennai-602024
*Author for the correspondence:
Department of Pharmaceutical Sciences,
Madras Medical College, Chennai-3.
E-mail: [email protected]
Alcohol and aqueous extract of Cadaba fruticosa (leaves) were subjected for hypoglycemic activity in wistar rats (160-200 g). The oral administration of leaf extracts at dose 1000 mg/kg led to a significant blood glucose reduction. Phytochemical analysis of alcohol extract revealed the presence of terpenoids, flavanoids, steroids, proteins, alkaloids, gums, sugars and saponins but negative result was observed in aqueous extract except terpenoids, flavonaids, proteins, furans, gums and sugars. This study brings out the evidence regarding pharmacological and phytochemical activities of C. fruticosa.
Keywords: Acute toxicity, anti-diabetic, alloxaninduced diabetes, Cadaba fruticosa
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