• P-ISSN 0974-6846 E-ISSN 0974-5645

Indian Journal of Science and Technology

Article

Indian Journal of Science and Technology

Year: 2022, Volume: 15, Issue: 9, Pages: 364-370

Review Article

Yoga and Rasayana for Mental Health in Age-related Cognitive Decline - A Controlled Trial

Received Date:12 January 2021, Accepted Date:28 January 2022, Published Date:05 March 2022

Abstract

Background: Age-related cognitive impairment has a negative impact on mental health in the elderly. Ayurveda Rasayana and yoga positively impact cognition and mental health among the elderly. Aims: Present study evaluated the efficacy of Ayurveda Medhya Rasayana (AMR) and Integrated Yoga (IY) on mental health in elderly individuals who had mild cognitive impairment. Materials and Methods: This is a three arms-matched control trial. The study involved 72 elderly subjects who had a mild cognitive impairment (MCI). Of these, 25 received IY, 23 received AMR and, 24 persons received combined (IY plus AMR) intervention for 8 weeks. Stress, anxiety, depression, quality of life, and sleep were assessed by using Perceived Stress Scale, Hamilton Anxiety Rating Scale, Geriatric Depression Scale, Quality of Life in the elderly (CASP- 19) and Pittsburg Sleep Quality Index respectively at baseline and after eight weeks. Results: ANOVA shows significant improvement (p<0.05) in quality of life, stress, anxiety, and sleep at eight weeks compared to baseline for all three groups. Depression was significantly improved only in IY plus AMR group. In the between-group comparison, ANCOVA was performed as baseline variable scores were not matched. It shows there was significant difference in groups for stress F (2, 69) = 6.439(p<0.003), anxiety F (2, 69) = 7.581 (p<0.001) and sleep Quality (2, 69) = 4.0449 (p<0.022). Bonferroni post hoc test shows IY plus AMR significantly better than AMR intervention in improving stress, anxiety, and sleep. Conclusion: Combined Ayurveda Medhya Rasayana and Integrated Yoga intervention are better to improve stress, anxiety, and sleep among elderly having mild cognitive impairment than individual treatment. However, further studies are warranted.

Keywords: Yoga; Traditional Herbal medicine; Medhya Rasayana; mental health; Brahmi; geriatric care

References

  1. Prince MJ, Wu F, Guo Y, Robledo LMG, O'Donnell M, Sullivan R, et al. The burden of disease in older people and implications for health policy and practice. The Lancet. 2015;385:549–562. Available from: https://dx.doi.org/10.1016/s0140-6736(14)61347-7
  2. Andreas S, Schulz H, Volkert J, Dehoust M, Sehner S, Suling A, et al. Prevalence of mental disorders in elderly people: The European MentDis_ICF65+ study. British Journal of Psychiatry. 2017;210(2):125–131. Available from: https://dx.doi.org/10.1192/bjp.bp.115.180463
  3. Canuto A, Weber K, Baertschi M, Andreas S, Volkert J, Dehoust MC, et al. Anxiety Disorders in Old Age: Psychiatric Comorbidities, Quality of Life, and Prevalence According to Age, Gender, and Country. The American Journal of Geriatric Psychiatry. 2018;26(2):174–185. Available from: https://dx.doi.org/10.1016/j.jagp.2017.08.015
  4. Guerra M, Prina AM, Ferri CP, Acosta D, Gallardo S, Huang Y, et al. A comparative cross-cultural study of the prevalence of late life depression in low and middle income countries. Journal of Affective Disorders. 2016;190:362–368. Available from: https://dx.doi.org/10.1016/j.jad.2015.09.004
  5. Eshkoor SA, Mun CY, Ng CK, Hamid TA. Mild cognitive impairment and its management in&nbsp;older people. Clinical Interventions in Aging. 2015;10:687. Available from: https://dx.doi.org/10.2147/cia.s73922
  6. Tuulio-Henriksson A, Perälä J, Saarni SI, Isometsä E, Koskinen S, Lönnqvist J, et al. Cognitive functioning in severe psychiatric disorders: a general population study. European Archives of Psychiatry and Clinical Neuroscience. 2011;261:447–456. Available from: https://dx.doi.org/10.1007/s00406-010-0186-y
  7. Saraçlı Ö, Akca ASD, Atasoy N, Önder Ö, Şenormancı Ö, Kaygisız İ, et al. The Relationship between Quality of Life and Cognitive Functions, Anxiety and Depression among Hospitalized Elderly Patients. Clinical Psychopharmacology and Neuroscience. 2015;13(2):194–200. Available from: https://dx.doi.org/10.9758/cpn.2015.13.2.194
  8. Chen C, Hu Z, Jiang Z, Zhou F. Prevalence of anxiety in patients with mild cognitive impairment: A systematic review and meta-analysis. Journal of Affective Disorders. 2018;236:211–221. Available from: https://dx.doi.org/10.1016/j.jad.2018.04.110
  9. Ismail Z, Elbayoumi H, Fischer CE, Hogan DB, Millikin CP, Schweizer T, et al. Prevalence of Depression in Patients With Mild Cognitive Impairment. JAMA Psychiatry. 2017;74:58. Available from: https://dx.doi.org/10.1001/jamapsychiatry.2016.3162
  10. McHugh RK, Whitton SW, Peckham AD, Welge JA, Otto MW. Patient Preference for Psychological vs Pharmacologic Treatment of Psychiatric Disorders. The Journal of Clinical Psychiatry. 2013;74:595–602. Available from: https://dx.doi.org/10.4088/jcp.12r07757
  11. Niclasen J, Lund L, Obel C, Larsen L. Mental health interventions among older adults: A systematic review. Scandinavian Journal of Public Health. 2019;47:240–250. Available from: https://dx.doi.org/10.1177/1403494818773530
  12. Sharma H, Chandola HM, Singh G, Basisht G. Utilization of Ayurveda in Health Care: An Approach for Prevention, Health Promotion, and Treatment of Disease. Part 2—Ayurveda in Primary Health Care. The Journal of Alternative and Complementary Medicine. 2007;13(10):1135–1150. Available from: https://dx.doi.org/10.1089/acm.2007.7017-b
  13. Abdelmagyd HAE, Shetty DSR, Al-Ahmari DMMM. Herbal medicine as adjunct in periodontal therapies- A review of clinical trials in past decade. Journal of Oral Biology and Craniofacial Research. 2019;9(3):212–217. Available from: https://dx.doi.org/10.1016/j.jobcr.2019.05.001
  14. Sharma R, Kabra A, Rao MM, Prajapati PK. Herbal and Holistic Solutions for Neurodegenerative and Depressive Disorders: Leads from Ayurveda. Current Pharmaceutical Design. 2018;24(22):2597–2608. Available from: https://dx.doi.org/10.2174/1381612824666180821165741
  15. Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. Effects of a Standardized Bacopa monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly: A Randomized, Double-Blind, Placebo-Controlled Trial. The Journal of Alternative and Complementary Medicine. 2008;14(6):707–713. Available from: https://dx.doi.org/10.1089/acm.2008.0018
  16. Mooventhan A, Nivethitha L. Evidence based effects of yoga practice on various health related problems of elderly people: A review. Journal of Bodywork and Movement Therapies. 2017;21(4):1028–1032. Available from: https://dx.doi.org/10.1016/j.jbmt.2017.01.004
  17. Balasubramaniam M, Telles S, Doraiswamy PM. Yoga on Our Minds: A Systematic Review of Yoga for Neuropsychiatric Disorders. Frontiers in Psychiatry. 2013;3. Available from: https://dx.doi.org/10.3389/fpsyt.2012.00117
  18. Eyre HA, Siddarth P, Acevedo B, Dyk KV, Paholpak P, Ercoli L, et al. A randomized controlled trial of Kundalini yoga in mild cognitive impairment. International Psychogeriatrics. 2017;29(4):557–567. Available from: https://dx.doi.org/10.1017/s1041610216002155
  19. Bonura KB, Tenenbaum G. Effects of Yoga on Psychological Health in Older Adults. Journal of Physical Activity and Health. 2014;11(7):1334–1341. Available from: https://dx.doi.org/10.1123/jpah.2012-0365
  20. Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, et al. The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. Journal of the American Geriatrics Society. 2005;53(4):695–699. Available from: https://dx.doi.org/10.1111/j.1532-5415.2005.53221.x
  21. Hamilton MA. The assessment of anxiety states by rating. . British journal of medical psychology. 1959;32:50–55. Available from: https://doi.org/10.1111/j.2044-8341.1959.tb00467.x
  22. Sheikh JI, Yesavage JA. Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. Clinical Gerontologist: The Journal of Aging and Mental Health. 1986;5(1-2):165–173. Available from: https://doi.org/10.1300/J018v05n01_09
  23. Cohen S, Kamarck T, Mermelstein R. A Global Measure of Perceived Stress. Journal of Health and Social Behavior. 1983;24:385. Available from: https://dx.doi.org/10.2307/2136404
  24. Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh sleep quality index: A new instrument for psychiatric practice and research. Psychiatry Research. 1989;28(2):193–213. Available from: https://dx.doi.org/10.1016/0165-1781(89)90047-4
  25. Manu P, Shetty SK, P SH. Critical review on effect of Bramhi Ghrita in Psychiatric Disorders. International Journal of Research in Ayurveda & Pharmacy. 2017;8(1):16–18. Available from: https://dx.doi.org/10.7897/2277-4343.08128
  26. Brahmananda T, Chikitsastana. Varanasi: subharatiprakashan. Commentary Caraka Chandrika (Hindi). 2009;p. 411.
  27. Murthy S, Uttarasthana. Chikitsastana. In: Commentary Caraka Chandrika (Hindi). (pp. 43) Varanasi. subharatiprakashan. 2004.
  28. Roodenrys S. Chronic Effects of Brahmi (Bacopa monnieri) on Human Memory. Neuropsychopharmacology. 2002;27(2):279–281. Available from: https://dx.doi.org/10.1016/s0893-133x(01)00419-5
  29. Bonura KB, Tenenbaum G. Effects of Yoga on Psychological Health in Older Adults. Journal of Physical Activity and Health. 2014;11(7):1334–1341. Available from: https://dx.doi.org/10.1123/jpah.2012-0365
  30. Bhavanani A, Ramanathan M, Trakroo M. Effect of a 12-week yoga therapy program on mental health status in elderly women inmates of a hospice. International Journal of Yoga. 2017;10:24. Available from: https://dx.doi.org/10.4103/0973-6131.186156
  31. Zimmerman ME, Ezzati A, Katz MJ, Lipton ML, Brickman AM, Sliwinski MJ, et al. Perceived Stress Is Differentially Related to Hippocampal Subfield Volumes among Older Adults. PLOS ONE. 2016;11(5):e0154530. Available from: https://dx.doi.org/10.1371/journal.pone.0154530
  32. Gangadhar B, Hariprasad V, Varambally S, Shivakumar V, Kalmady S, Venkatasubramanian G. Yoga increases the volume of the hippocampus in elderly subjects. Indian Journal of Psychiatry. 2013;55(7):394. Available from: https://dx.doi.org/10.4103/0019-5545.116309
  33. Balasubramaniam M, Telles S, Doraiswamy PM. Yoga on Our Minds: A Systematic Review of Yoga for Neuropsychiatric Disorders. Frontiers in Psychiatry. 2013;3. Available from: https://dx.doi.org/10.3389/fpsyt.2012.00117
  34. Harvey R, Andriopoulou P, Grogan S. Perceived mechanisms of change in therapeutic yoga targeting psychological distress. Journal of Bodywork and Movement Therapies. 2020;24(1):274–280. Available from: https://dx.doi.org/10.1016/j.jbmt.2019.06.014
  35. Bhattacharya SK, Bhattacharya A, Kumar A, Ghosal S. Antioxidant activity ofBacopa monniera in rat frontal cortex, striatum and hippocampus. Phytotherapy Research. 2000;14(3):174–179. Available from: https://dx.doi.org/10.1002/(sici)1099-1573(200005)14:3<174::aid-ptr624>3.0.co;2-o

Copyright

© 2022 Chobe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Published By Indian Society for Education and Environment (iSee)

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