A Comparative Study of Severity of Covid-19 Infection & their Radiological Findings in Vaccinated and Unvaccinated Individuals

S Moogaambiga; Chittimalla Pranay; K Kirubhakaran; S R Rangabashyam; Lakhan Parajiya

doi:10.17485/IJST/v15i40.899

Article

A Comparative Study of Severity of Covid-19 Infection & their Radiological Findings in Vaccinated and Unvaccinated Individuals

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Indian Journal of Science and Technology

DOI: 10.17485/IJST/v15i40.899

Year: 2022, Volume: 15, Issue: 40, Pages: 2103-2108

Original Article

A Comparative Study of Severity of Covid-19 Infection & their Radiological Findings in Vaccinated and Unvaccinated Individuals

S Moogaambiga¹, Chittimalla Pranay^2*, K Kirubhakaran¹, S R Rangabashyam³, Lakhan Parajiya⁴

¹Associate Professor, Department of General Medicine, Vinayaka Mission, Kirupananda Variyar, Salem, TamilNadu, India
²Junior Resident, Department of General Medicine, Vinayaka Mission, Kirupananda Variyar Salem, Tamil Nadu, India
³Professor, Department of General Medicine, Vinayaka Mission, Kirupananda Variyar Salem, Tamil Nadu, India
⁴Senior Resident, Department of General Medicine, Vinayaka Mission, Kirupananda Variyar Salem, Tamil Nadu, India

*Corresponding Author
Email: [email protected]

Received Date:27 July 2022, Accepted Date:06 September 2022, Published Date:31 October 2022

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Objectives: To compare the severity of COVID-19 infection and their radiological findings between vaccinated and unvaccinated individuals. Also, to investigate if any difference of severity of infection exists between patients with blood group ‘A’ and with blood group ‘O’. Methods: This study has 302 patients which include both vaccinated and unvaccinated individuals. Both the group of patients were subjected to Computed tomography-Chest imaging and the severity of COVID-19 infection was analyzed between both the groups using CT-Severity score (CT-SS). Findings: In 302 study population, 91% of patients are unvaccinated and remaining 9% are vaccinated. Among these patients, 273 were having CORADS-5 which constitute 90% of population. Mortality among unvaccinated people was 17.2% compared to vaccinated people having mortality rate of 3.4% which was significant. Individuals with Blood group ‘A’ were highly infected and individuals with group ‘O’ were least affected compared to individuals with other blood groups among unvaccinated individuals. Novelty: Increased mortality was seen among unvaccinated individuals( 17.2%)compared to vaccinated patients(3.4%). CT-Severity score was lower among vaccinated patients compared to unvaccinated patients. This study also compared the severity of the infection in individuals with various ABO blood groups among unvaccinated patients which showed that there was a significant effect on blood groups on severity of infection.

Keywords: COVID19; Vaccination; CTSeverity score; ABO Blood grouping; Mortality

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Copyright

2022 Moogaambiga et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Indian Society for Education and Environment (iSee)