Indian Journal of Science and Technology

Abstract

We have evaluated antioxidant and antimicrobial activities of various solvents extracts from Pleurotus ostreatus. Organic solvents such as acetone, ethyl acetate, and ethanol were used to produce P. ostreatus extracts. Antioxidant activities were determined by measuring total polyphenol and flavonoid contents, DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) radical scavenging activity, and ABTS (2,2’-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activity. The acetone extract showed the highest antioxidant activities except total flavonoid contents. Antimicrobial activities of P. ostreatus extracts were determined against four strains of Gram-negative bacteria and eleven strains of Gram-positive bacteria including nine oral bacteria by disc diffusion method. The acetone extracts had antimicrobial activities against only B. subtilis and E. coli, whereas the other extracts inhibited the growth of most oral bacteria. These extracts showed a significant growth inhibition against S. sanguinis.
Keywords: ABTS Radical Scavenging Activity, Antioxdant Activity, Antimicrobial Activity, DPPH Radical Scavenging Activity, Pleurotus Ostreatus (Oyster Mushroom)