Exploration of the Mizo Traditional Medicine: Pharmacognostic Studies of the Indigenous Medicinal Plant, Erythrina stricta

Lucy Lalawmpuii; Lalbiakngheti Tlau; P B Lalthanpuii; K Lalchhandama

doi:10.17485/IJST/v16sp1.msc1

Article

Exploration of the Mizo Traditional Medicine: Pharmacognostic Studies of the Indigenous Medicinal Plant, Erythrina stricta

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Indian Journal of Science and Technology

DOI: 10.17485/IJST/v16sp1.msc1

Year: 2023, Volume: 16, Issue: Special Issue 1, Pages: 1-9

Original Article

Exploration of the Mizo Traditional Medicine: Pharmacognostic Studies of the Indigenous Medicinal Plant, Erythrina stricta

Lucy Lalawmpuii¹, Lalbiakngheti Tlau¹, P B Lalthanpuii¹, K Lalchhandama^1*

¹Department of Life Sciences, Pachhunga University College, Aizawl, 796001, Mizoram, India

*Corresponding Author
Email: [email protected]

Received Date:23 January 2023, Accepted Date:09 June 2023, Published Date:30 July 2023

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Objectives: The study aimed to understand the range of medicinal applications of Erythrina stricta Roxb. (Fabaceae) among the Mizo people of India, and to analyse the pharmacological properties of the bark extract. Methods: Ethnomedicinal investigation was conducted among traditional healers and users. The petroleum ether extract of the bark was analysed for its phytochemical components. Antioxidant property was evaluated by DPPH (2,2- diphenyl-1-picrylhydrazyl) radical scavenging assay. Total antioxidant capacity, flavonoid and total phenolic contents of the plant extract were assessed by using the phosphomolybdate method, Folin-Ciocalteu assay and aluminium chloride assay respectively. Antimicrobial activity was tested on two Gramnegative and four Gram-positive bacteria. Findings: E. stricta was used for the treatment of stomach ulcer, diabetic blisters, intestinal roundworm infection, skin infection, sores and wounds. The plant extract contained phytochemicals like alkaloids, flavonoids, phenols, tannins, amino acids and proteins, phytosterols and triterpenoids. The extract showed concentrationdependent antioxidant activity against DPPH; showing an IC50 value of 3.330.024 mg/ml compared to 0.230.095 mg/ml for the reference butylated hydroxytoluene. The total antioxidant capacity was 12.010.33 mg ascorbic acid equivalent per gram (AAE/g) of the dry extract; the total phenolic content was 3.770.12 mg gallic acid equivalent per gram (GAE/g) of the dry extract; while the total flavonoid content was 7.751.13 mg quercetin equivalent per gram (QE/g) of the dry extract. The extract effectively inhibited the growth of two Gram-positive bacteria, Bacillus cereus and Staphylococcus aureus, and one Gram-negative species, Klebsiella pneumoniae. Novelty: E. stricta was found to have important medicinal applications and pharmacological potential, and needs systematic conservation and propagation. It showed high antioxidant values, and species-specific antibacterial activities.

Keywords: Erythrina stricta; antioxidant activity; antibacterial activity; medicinal plant; phytochemical

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© 2023 Lalawmpuii et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Indian Society for Education and Environment (iSee)