• P-ISSN 0974-6846 E-ISSN 0974-5645

Indian Journal of Science and Technology

Article

Indian Journal of Science and Technology

Year: 2024, Volume: 17, Issue: 1, Pages: 16-25

Original Article

Multi-Component Exercise Programme for Sarcopenia and Frailty Population - An Observational Study

Received Date:16 August 2023, Accepted Date:07 November 2023, Published Date:05 January 2024

Abstract

Objectives: To find out the effect of multicomponent exercise programme on sarcopenia and frailty in elderly population. Methods: This was an observational study. The elderly population with an age group of >60 years residing in villages within 10–15 km of Sumandeep Vidyapeeth, Vadodara, India, was considered in the study. The study population consisted of 205 participants who were diagnosed with sarcopenia and frailty during phase 1 of the study. The study was conducted from August 2022 to May 2023. The participants were placed on a multicomponent exercise programme that included resistance training exercises, balance exercises, flexibility exercises, and endurance exercises. Grip strength, muscle mass, appendicular skeletal muscle mass (ASM), skeletal muscle index (SMI), calf circumference (CC), gait speed, and frailty were assessed at the end of 4 weeks, 8 weeks, and 12 weeks. Microsoft Excel and STATA-IC statistical software, version 13, were used to analyse the data. Findings: A total of 59 participants adhered to exercises for 12 weeks. Mauchly’s sphericity test showed a statistically significant change in ASM and SMI (P = 0.001). In the subject effects over a duration of 4 to 12 weeks, there was no statistically significant difference found in grip strength (p = 0.257), right CC (p = 0.114), ASM (p = 0.109), SMI (p = 0.052), and gait speed (p = 0.641). At the end of 12 weeks, there was a reduction in the status of frailty 1.7% "frail," 6% "pre-frail,” and 91.5% “no frail” as compared to 3.4%, 8.5%, and 88.1%, respectively at 4 weeks. Conclusion: In the present study, multicomponent exercise programme had no statistically significant effect on sarcopenia (grip strength, muscle mass, or gait speed) according to the follow-up data from weeks 4 to 12. Despite this, a 12-week exercise programme improved the frailty status. Novelty: This study is one of its kind where elderly population having Sarcopenia and Frailty were given exercise programme for 12-weeks of duration at their doorsteps in the community.

Keywords: Sarcopenia, Frailty, Exercise, Older adults, Multicomponent Exercise

References

  1. Hurst C, Robinson SM, Witham MD, Dodds RM, Granic A, Buckland C, et al. Resistance exercise as a treatment for sarcopenia: prescription and delivery. Age and Ageing. 2022;51(2):1–10. Available from: https://doi.org/10.1093/ageing/afac003
  2. Tyrovolas S, Koyanagi A, Olaya B, Ayuso‐mateos JL, Miret M, Chatterji S, et al. Factors associated with skeletal muscle mass, sarcopenia, and sarcopenic obesity in older adults: a multi‐continent study. Journal of Cachexia, Sarcopenia and Muscle. 2016;7(3):312–321. Available from: https://doi.org/10.1002/jcsm.12076
  3. Kumar P, Umakanth S, Girish N. A review of the components of exercise prescription for sarcopenic older adults. European Geriatric Medicine. 2022;13(6):1245–1280. Available from: https://doi.org/10.1007/s41999-022-00693-7
  4. Rodrigues F, Domingos C, Monteiro D, Morouço P. A Review on Aging, Sarcopenia, Falls, and Resistance Training in Community-Dwelling Older Adults. International journal of environmental research and public health. 2022;19(2):1–11. Available from: https://doi.org/10.3390/ijerph19020874
  5. Colleluori G, Aguirre L, Phadnis U, Fowler K, Armamento-Villareal R, Sun Z, et al. Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss. Cell Metabolism. 2019;30(2):261–273. Available from: https://doi.org/10.1016/j.cmet.2019.06.008
  6. Moore SA, Hrisos N, Errington L, Rochester L, Rodgers H, Witham M, et al. Exercise as a treatment for sarcopenia: an umbrella review of systematic review evidence. Physiotherapy. 2020;107:189–201. Available from: https://doi.org/10.1016/j.physio.2019.08.005
  7. Lozano-Montoya I, Correa-Pérez A, Abraha I, Soiza RL, Cherubini A, O'mahony D, et al. Nonpharmacological interventions to treat physical frailty and sarcopenia in older patients: a systematic overview – the SENATOR Project ONTOP Series. Clinical Interventions in Aging. 2017;12:721–740. Available from: https://doi.org/10.2147/CIA.S132496
  8. Tyrovolas S, Koyanagi A, Olaya B, Ayuso-Mateos JL, Miret M, Chatterji S, et al. The role of muscle mass and body fat on disability among older adults: A cross-national analysis. Experimental Gerontology. 2015;69:27–35. Available from: https://doi.org/10.1016/j.exger.2015.06.002
  9. Cadore EL, Izquierdo M. Muscle Power Training: A Hallmark for Muscle Function Retaining in Frail Clinical Setting. Journal of the American Medical Directors Association. 2018;19(3):190–192. Available from: https://doi.org/10.1016/j.jamda.2017.12.010
  10. Bernabei R, Landi F, Calvani R, Cesari M, Signore SD, Anker SD, et al. Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project) BMJ. 2022;377:1–13. Available from: https://doi.org/10.1136/bmj-2021-068788
  11. Lopez P, Pinto RS, Radaelli R, Rech A, Grazioli R, Izquierdo M. Benefits of resistance training in physically frail elderly: a systematic review. Aging clinical and experimental research. 2018;30:889–899. Available from: https://doi.org/10.1007/s40520-017-0863-z
  12. Dent E, Daly RM, Hoogendijk EO, Scott D. Exercise to Prevent and Manage Frailty and Fragility Fractures. Current Osteoporosis Reports. 2023;21(2):205–215. Available from: https://doi.org/10.1007/s11914-023-00777-8
  13. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age and Ageing. 2019;48(1):16–31. Available from: https://doi.org/10.1093/ageing/afy169
  14. Kawakami R, Murakami H, Sanada K, Tanaka N, Sawada SS, Tabata I, et al. Calf circumference as a surrogate marker of muscle mass for diagnosing sarcopenia in Japanese men and women. Geriatrics & Gerontology International. 2015;15(8):969–976. Available from: https://doi.org/10.1111/ggi.12377
  15. Shettigar S, Shivaraj K, Shettigar S. A Study to Assess the Factors Affecting Adherence to Exercise in the Indian Population. Cureus. 2019;11(11). Available from: https://doi.org/10.7759/cureus.6062
  16. Pallavi Y, Dwivedi P, Anthony SL. Exercise Adherence Following Physiotherapy Interventions in Older Adults 60 Yrs and Above - A Descriptive Study. International Journal of Science and Research (IJSR). 2021;10(9):772–776. Available from: https://www.ijsr.net/archive/v10i9/SR21914225443.pdf
  17. Hwang J, Park S. Gender-Specific Risk Factors and Prevalence for Sarcopenia among Community-Dwelling Young-Old Adults. International Journal of Environmental Research and Public Health. 2022;19(12):1–9. Available from: https://doi.org/10.3390/ijerph19127232
  18. Bohannon RW. Grip Strength: An Indispensable Biomarker For Older Adults. Clinical Interventions in Aging. 2019;14:1681–1691. Available from: https://doi.org/10.2147/CIA.S194543
  19. Schaap LA, Fox B, Henwood T, Bruyère O, Reginster JYY, Beaudart C, et al. Grip strength measurement: Towards a standardized approach in sarcopenia research and practice. European Geriatric Medicine. 2016;7(3):247–255. Available from: https://doi.org/10.1016/j.eurger.2015.11.012
  20. Kumar P, Nayak K, Umakanth S, Girish N. Effect of targeted intervention on C-terminal agrin fragment and its association with the components of sarcopenia: a scoping review. Aging Clinical and Experimental Research. 2023;35(6):1161–1186. Available from: https://doi.org/10.1007/s40520-023-02396-w
  21. Volpi E, Nazemi R, Fujita S. Muscle tissue changes with aging. Current opinion in clinical nutrition and metabolic care. 2004;7(4):405–410. Available from: https://doi.org/10.1097/01.mco.0000134362.76653.b2
  22. Vlietstra L, Hendrickx W, Waters DL. Exercise interventions in healthy older adults with sarcopenia: A systematic review and meta-analysis. Australasian Journal on Ageing. 2018;37(3):169–183. Available from: https://doi.org/10.1111/ajag.12521
  23. Sadjapong U, Yodkeeree S, Sungkarat S, Siviroj P. Multicomponent Exercise Program Reduces Frailty and Inflammatory Biomarkers and Improves Physical Performance in Community-Dwelling Older Adults: A Randomized Controlled Trial. International Journal of Environmental Research and Public Health. 2020;17(11):1–15. Available from: https://doi.org/10.3390/ijerph17113760
  24. Ji L, Jazwinski SM, Kim S. Frailty and Biological Age. Annals of geriatric medicine and research. 2021;25(3):141–149. Available from: https://doi.org/10.4235/agmr.21.0080

Copyright

© 2024 Gupta et al.  This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Indian Society for Education and Environment (iSee)

DON'T MISS OUT!

Subscribe now for latest articles and news.