Indian Journal of Science and Technology
DOI: 10.17485/ijst/2019/v12i15/143143
Year: 2019, Volume: 12, Issue: 15, Pages: 1-7
Original Article
Abeer Abdulaziz H. Bukhari*
Department of Chemistry, Faculty of Science, University of Tabuk, Saudi Arabia; [email protected]
*Author for correspondence
Abeer Abdulaziz H. Bukhari
Department of Chemistry, Faculty of Science, University of Tabuk, Saudi Arabia.
Email: [email protected]
Objective: To prepare Chitosan-Multi Walled Carbon Nanotube (Ch: MWCNT) nanocomposite with different chitosan: MWCNT ratios were successfully prepared by modifying chitosan and functionalized MWCNT. Methods: The prepared Ch-MWCNTs nanocomposite was characterized by TEM analysis confirming the MWCNTs homogenously distributed in chitosan matrix. Furthermore, TEM results indicate the resulting MWCNT tubular length morphology. Based on the FTIR results which confirm the presence of the C = C. The FTIR indicates that the characteristic functional groups of MWCNTs and chitosan are successfully present in modified nanocomposite. Findings/Application: Nanocomposite Ch/MWCNT showed higher antimicrobial activity against both Gram negative and Gram positive bacteria. The nanocomposites are highly differentiable at the lower conc. as even only 1% conc. from multifunctional nanocomposite has found to be very effective against the target microorganisms. Minimal Inhibitory Concentrations (MIC) of Ch-MWCNT (100:50 Ch/MWCNT) against Gram negative and Gram positive pathogenic bacteria between 0.5 and 0.0625 μl, and the growth inhibition effect has been observed in a concentration-dependent species.
Keywords: Antimicrobial, Chitosan, CNT, Nanocomposites
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