• P-ISSN 0974-6846 E-ISSN 0974-5645

Indian Journal of Science and Technology

Article

Relationship Between Glycosylated Haemoglobin and Dyslipidaemia in Individuals Exposed to COVID-19: A Cross Sectional Study in North Indian Population
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Indian Journal of Science and Technology

DOI: 10.17485/IJST/v16i43.208

Year: 2023, Volume: 16, Issue: 43, Pages: 3911-3916

Original Article

Relationship Between Glycosylated Haemoglobin and Dyslipidaemia in Individuals Exposed to COVID-19: A Cross Sectional Study in North Indian Population

Ashok Kumar1, M Vijayasimha2*, Nioly Sarkar3, M Srikanth4, Pranav Prakash5, Neha Chandel6

1Department of Medical Laboratory Science, G D Goenka University, Gurugram, Haryana, India
2Department of Medical Laboratory Technology, The Neotia University, Kolkata, India
3School of Health Sciences, The Neotia University, Kolkata, India
4Swaroop Multispecility Hospital, Laksar, Haridwar, India
5Department of public health, GD Goenka University, Sohna, Haryana, India
6Department of MLT, School of medical lab sciences, GD Goenka University, Sohna, Haryana, India

*Corresponding Author
Email: [email protected]

Received Date:29 January 2023, Accepted Date:08 October 2023, Published Date:17 November 2023

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Objective: To investigate the correlation between Glycosylated Hemoglobin and dyslipidemia in individuals exposed to COVID-19 in the Delhi/NCR region. Method: In the Delhi/NCR region, a total of 521 patient fasting blood samples were gathered from a NABL Accredited labs. These samples, collected between July 2020 and March 2022, consisted of 334 males and 187 females. HbA1C and lipid profile tests for the patients were conducted using conventional methods at a laboratory located in Gurugram. Findings: Among diabetic patients below 40 years of age, the mean HDL levels decreased to 40.3% compared to 42 mg/dl in non-diabetics. Increased glycosylated hemoglobin [more than 7%] with dyslipidemia noted in males 114 compared to females 64. A significant decrease in HDL levels were observed in diabetic patients above 40 years of age, with the mean level of HDL dropping to 33 mg/dl. The dyslipidemia was present in 80.9% of male diabetic patients and 88.6% of female diabetic patients. In diabetic male patients, a correlation between increasing triglyceride levels and the decreased HDL levels found. The mean triglyceride level in diabetic patients was 199 mg/dl, while the mean HDL level was 42 mg/dl. On the other hand, non-diabetic individuals had a mean triglyceride level of 105 mg/dl and an HDL level of 44 mg/dl. Novelty: Dyslipidemia is significantly associated with poorly controlled HbAa1c in T2DM than non-diabetic subjects after covid exposure. This observation points towards a U-shaped correlation between HDL and glycated haemoglobin in diabetic patients.

Keywords: Glycosylated haemoglobin, Dyslipidemia, Cardivascular disease, High density lipoprotein Diabetes mellitus (DM), coronary heart disease (CHD)

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Copyright

© 2023 Kumar et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Indian Society for Education and Environment (iSee)

  • 18 November 2023

Year: 2023, Volume: 16, Issue: 43

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