Indian Journal of Science and Technology
Year: 2008, Volume: 1, Issue: 6, Pages: 1-8
Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh, Pittsburgh, PA 15260.
Author for the correspondence:
Pittsburgh Institute for Neurodegenerative Diseases,
University of Pittsburgh, Pittsburgh, PA 15260.
E-mail: [email protected]
The nematode Caenorhabditis elegans is an important, well-studied organism used in biomedical research as a model for human development, genetics, ageing, and disease. This paper reviews some basic information, recent progress and future challenges for functional genomics and bioinformatics in the area of alternative splicing. It also highlights the unique methodology adopted by us to study and to detect novel alternatively spliced transcripst from C. elegans genome.
Keywords: Alternative splicing, Caenorhabditis elegans, gene/exon prediction, genome analysis.
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