Evaluation of Antioxidant and Antibacterial Property of Microwave Assisted Green Synthesis of Fe3O4 -MgO Nanocomposites

Lakkappa B Anigol; Vinodkumar P Sajjan; Prabhuodeyara M Gurubasavaraj

doi:10.17485/IJST/v16i24.629

Article

Evaluation of Antioxidant and Antibacterial Property of Microwave Assisted Green Synthesis of Fe3O4 -MgO Nanocomposites

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Indian Journal of Science and Technology

DOI: 10.17485/IJST/v16i24.629

Year: 2023, Volume: 16, Issue: 24, Pages: 1777-1786

Original Article

Evaluation of Antioxidant and Antibacterial Property of Microwave Assisted Green Synthesis of Fe3O4 -MgO Nanocomposites

Lakkappa B Anigol¹, Vinodkumar P Sajjan¹, Prabhuodeyara M Gurubasavaraj^1*

¹Department of Chemistry, Rani Channamma University, Vidyasangama, PBNH-04, Belagavi, 591156, Karnataka, India

*Corresponding Author
Email: [email protected]

Received Date:18 March 2023, Accepted Date:01 June 2023, Published Date:19 June 2023

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Objectives: To synthesize Magnesium oxide, iron oxide nanoparticles and Fe₃O₄-MgO nanocomposite using agro waste of lemon peel extract (LPE) and to examine their antioxidant and antibacterial activity. Methods: MgO, Fe₃O₄ NPs and Fe₃O₄–MgO nanocomposite by microwave-assisted technique using LPE. Feature techniques such as UV-Visible spectroscopy, X-ray diffraction (XRD), Thermo gravimetric analysis (TGA) and Scanning electron microscope (SEM) were performed to characterize the prepared material in terms of morphology and structure. Furthermore, Fourier transform infrared (FTIR) spectroscopy analysis was used to identify the possible functional groups present in the synthesis of MgO, Fe₃O₄ NPs and Fe₃O₄-MgO nanocomposite. Finding: Powder XRD confirmed the formation of MgO, Fe₃O₄ NPs and Fe₃O₄- MgO nanocomposite, SEM analysis confirmed that Iron oxide and Magnesium oxide nanoparticles and Fe₃O₄-MgO nanocomposite are mostly in spherical shape, while TG analysis indicated the greater thermal stability of nanoparticles as well as nanocomposite. All Synthesized nanoparticles and nanocomposite showed good antibacterial activity against gram positive and gram-negative bacterial strains (IC50 value are 8.32, 8.15 & 8.13 and 7.23, 7.57 & 7.47 mg/mL respectively). These metal oxide NPs showed antioxidant activities against DPPH (less than 85%) but enhancing activity was found for Fe₃O₄- MgO nanocomposite (89.95%). Novelty: These results suggested that LPE derived Fe₃O₄-MgO nanocomposites can be used as an effective antioxidant and antibacterial agent in biomedical applications.

Keywords: Lemon Peels Extract; Green Synthesis; Nanocomposites; Antioxidant Activity; Hemolytic Assay; Antibacterial Activity

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Copyright

© 2023 Anigol et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Indian Society for Education and Environment (iSee)