Indian Journal of Science and Technology
Year: 2009, Volume: 2, Issue: 3, Pages: 1-4
A. Vetrivel Rajan1 , N. Shanmugavalli2*, C. Greety Sunitha3 and V. Umashankar2
1Biocon India Pvt. Ltd., Bangalore;
2Dept. of Bioinformatics, SRM University, Chennai, India
3PG Dept. of Biochemistry, VHNSN College,Virudhunagar, India
*Author for the correspondence:
Dept. of Bioinformatics, SRM University,
E-mail: [email protected]
The objective of the present study is to determine the hepatoprotective effects of Cassia tora against carbon tetra chloride induced liver damage in albino rats. The efficacy of the treatment was estimated by the serum level marker enzymes: serum glutamatic oxaloacetic transaminase, serum glumate pyruvate transaminase and lactate dehydrogenase. The treatment also includes the estimation of enzymatic antioxidants: superoxide dismutase, glutathione peroxidase, glutathione-S transferase and catalase; non-enzymatic antioxidants: vitamin C and vitamin E. The results of this study reveal the remarkable increase of marker enzymes in induced rats and decreased level in cassia torra treated ones. Furthermore, the level of enzymatic and non-enzymatic antioxidant level were elevated in treated rats compared to induced ones.
Keywords: Antioxidants, Cassia tora, CCl4, liver damage, albino rats.
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