Nanocomposites Based on Polymer and Hydroxyapatite for Drug Delivery Application

M  Sundar Raj; V  H  Arkin; Adalarasu  and M  Jagannath

doi:10.17485/ijst/2013/v6isp5.18

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Nanocomposites Based on Polymer and Hydroxyapatite for Drug Delivery Application

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Indian Journal of Science and Technology

DOI: 10.17485/ijst/2013/v6isp5.18

Year: 2013, Volume: 6, Issue: Supplementary 5, Pages: 1-6

Original Article

Nanocomposites Based on Polymer and Hydroxyapatite for Drug Delivery Application

M. Sundar Raj^1* , V. H. Arkin² , Adalarasu³ and M. Jagannath⁴

¹Asst. Professor, Biomedical Engineering, [email protected]
²R & D Engineer, URILAB Systems- Diagnostics, [email protected]
³Professor, Department of ECE, PSNACET, [email protected]
4 Prof & Head - BME, SMK Fomra Institute of Technology, [email protected]
*Author For Correspondence
M. Sundar Raj
Asst. Professor, Biomedical Engineering,
Email: [email protected]

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

This research paper tells about sustained delivery of small molecular drug ciprofloxacin using hydroxyapatite hybrid poly (vinyl alcohol) nanocomposites. Hydroxyapatite - poly (vinyl alcohol) nanocomposites are used as a vehicle to carry drug, protein, implantable materials etc. In situ synthesized hydroxyapatite hybrid poly (vinyl alcohol) matrix was characterized using different characterization techniques like XRD, SEM and FTIR. Small molecular drug ciprofloxacin was loaded into hydroxyapatite hybrid poly (vinyl alcohol) nanocomposites. The morphology of drug free and drug loaded hydroxyapatite concoction poly (vinyl alcohol) nanocomposites is observed using SEM. In-vitro drug release is quantified using UV/VIS spectrophotometer. Keywords: Hydroxyapatite (HAP), Poly (Vinyl Alcohol) (PVA), Ciprofloxacin, Nanocomposites, Sustained Release, Drug Delivery, X-ray Diffraction (XRD), Scanning Electron Microscope (SEM).