Indian Journal of Science and Technology
Year: 2010, Volume: 3, Issue: 12, Pages: 1229-1236
Olawole O. Obembe* , Jacob O. Popoola, Sadhu Leelavathi1 and V. Siva Reddy1
Department of Biological Sciences, Covenant University, PMB 1023 Ota, Ogun State, Nigeria.
1 Plant Transformation Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.
Plastid transformation offers a viable alternative to nuclear transformation because of its numerous advantages. It was against this backdrop that various groups of researchers have been exploiting this group of sub-cellular organelles, over the last two decades, for the genetic engineering of agronomic traits and metabolic pathways, as well as for molecular farming for the production of plant-derived high-valued biopharmaceuticals and industrial proteins. In this short review, we discuss the evolution and development of this technology with respect to the current state-of-the-art, which places it in high pedestal as a cost effective and safe production technology for high quality molecular farming products as well as a highly efficient method to create new metabolic pathways and improve the agronomic traits.
Keywords: Chloroplast transformation, molecular farming, metabolic engineering, agronomic trait engineering
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