Indian Journal of Science and Technology
Year: 2009, Volume: 2, Issue: 11, Pages: 11-13
R. Amutha, Padmakrishnan1 , T. Murugan2 and M.P. Renuga devi2
Department of Biotechnology, VELS University, Pallavaram, Chennai-600117, India
1Department of Microbiology, Dr ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai -600 113.
2Department of Microbiology, SRM college of Arts and Science,Kattankulathur-603203, Tamilnadu, India
*Author for the correspondence:
Department of Biotechnology, VELS University
Pallavaram, Chennai-600117, India
E-mail: [email protected]
A total of 53 isolates of Pseudomonas aeruginosa were obtained from 250 clinical samples from pediatric populations in Chennai. The isolates were obtained from clinical specimens viz. the throat swab, ear swab and urine sample. The isolates of P. aeruginosa were subjected to antibiotic sensitivity test. Among various antibiotics tested, the strains showed highest resistance to ampicillin (85%), followed by amikacin (62.2%), norfloxacin (60.3%) and ciprofloxacin (50.9%). The data on ESBL production indicated overall production of 25% among MDR strains. MIC values for the antibiotics ranged from 3.9 µg/ml to 256µg/ml. These data suggest that the prevalence of ESBLs which are very important as these strains may often cause outbreaks in the pediatric population and causes increased morbidity and mortality in patients underlying diseases or limit therapeutic options due to the high degree of multidrug resistance.
Keywords: Multidrug resistant, Pseudomonas aeruginosa, ESBL, MIC, India.
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