Temperature Index of Antiviral Drugs Used to Combat Viral Diseases

Annmaria Baby; D Antony Xavier; A Theertha Nair; Eddith Sarah Varghese; S Akhila

doi:10.17485/IJST/v16iSP3.icrtam271

Article

Temperature Index of Antiviral Drugs Used to Combat Viral Diseases

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Indian Journal of Science and Technology

DOI: 10.17485/IJST/v16iSP3.icrtam271

Year: 2023, Volume: 16, Issue: Special Issue 3, Pages: 64-74

Original Article

Temperature Index of Antiviral Drugs Used to Combat Viral Diseases

Annmaria Baby^1*, D Antony Xavier², A Theertha Nair¹, Eddith Sarah Varghese¹, S Akhila¹

¹Research Scholar, Department of Mathematics, Loyola College, University of Madras, Chennai, Tamil Nadu, India
²Assistant Professor, Department of Mathematics, Loyola College, University of Madras, Chennai, Tamil Nadu, India

*Corresponding Author
Email: [email protected]

Received Date:13 February 2023, Accepted Date:11 August 2023, Published Date:04 December 2023

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Objective: To determine the temperature indices for antiviral drugs updated in WHO Disease Outbreak News such as Zika virus, Smallpox and Henipaviruses. Further, applying a regression analysis, the determined results can be used as a property predictive tool. Method: The degree counting techniques and edge partition approach is employed for computation of the temperature indices and applying the least square procedure the regression analysis model is extracted. Findings: The quantitative values of temperature indices for antiviral drugs used in treatment of few viral diseases are computed and a regression analysis based on the determined values are carried out in order to use as a property prediction tool. Novelty: Drug development and design have greatly benefited from the application of chemical graph theory. Temperature indices are pure mathematical descriptions of a molecular structure, which can be used as predictive tool in QSPR/QSAR research. The temperature indices for various chemical structures are being studied by researchers in order to obtain improved property-index correlation compared to that of those obtained through other topological indices.

Keywords: Temperature indices, Zika virus, Smallpox, Henipavirus, Antiviral drugs, Comparative analysis, Regression analysis

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Copyright

© 2023 Baby et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Published By Indian Society for Education and Environment (iSee)